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All analyses were conducted using SAS (version 9.3)

The rate of oral cancer registrations for Hull was 12% higher than England, and the rate of cancer registrations for oesophageal cancer was 22% higher than England and the highest across the region

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Additionally, studies have shown that nicotine causes an increase in stomach acid secretion, which can exacerbate underlying causes of stomach upset such as ulcers or gastritis