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(D) Western blots were performed, and (E) the relative protein levels of Sp1, SIRT1, acetyl-HIF-1, HIF-1, p21, and p27 in MLE-12 cells were determined (n = 3)
The HWL theme viewed did not have a significant influence on the pre-post change

Kaijuan Wang, ScienceDirect 2024

Its etiology and pathophysiology have not been fully elucidated and are likely multifactorial

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The quick answer is, yes, it can
