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Aim for 64 to 80 ounces of water daily, sipped throughout the day rather than consumed in large amounts

15 mg equals 0.375 mL (about 38 units)

Not in bed for 7 to 9 hours

The complexity of simultaneous GIP and GLP-1 receptor activation may create safety signals that are not apparent in shorter studies

Smallpox/Monkeypox vaccination and developed complications Wait 14 days after all vaccine complications have resolved or 8 weeks (56 days) from the date of having had the smallpox vaccination whichever is the longer period of time

Contact your GP or diabetes care team if you experience: Persistent nausea or vomiting lasting more than 2448 hours, particularly if unable to keep fluids down Signs of dehydration , including dark urine, dizziness, dry mouth, reduced urination, or confusion Severe or persistent abdominal pain , especially if accompanied by vomiting, which could indicate pancreatitis (a rare but serious side effect) Right upper abdominal pain, fever or yellowing of the skin/eyes , which may indicate gallbladder problems (cholelithiasis or cholecystitis) Symptoms of hypoglycaemia that do not resolve with usual treatment, or frequent episodes requiring assistance Unusual skin reactions at injection sites, including spreading redness, warmth, swelling, or discharge suggesting infection New or worsening symptoms following sun exposure that seem disproportionate to the level of exposure Seek immediate medical attention (call 999 or attend A&E) if you develop: Severe allergic reactions , including difficulty breathing, swelling of the face or throat, or widespread rash Signs of severe dehydration , such as extreme weakness, rapid heartbeat, very low blood pressure, or altered consciousness Symptoms of diabetic ketoacidosis , including excessive thirst, frequent urination, confusion, fruity-smelling breath, or rapid breathing (more common with insulin deficiency or in those also taking SGLT2 inhibitors) Severe, unrelenting abdominal pain with vomiting, which may indicate acute pancreatitis Patients should maintain regular contact with their diabetes care team and attend scheduled review appointments