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The GIP pathway was historically considered less pharmacologically useful than GLP-1 because early work suggested the receptor became less responsive in metabolic-disease states

Differently, administration of Citrobacter rodentium , a bacterium able to disrupt the epithelial barrier, in NOD mice, could increase intestinal permeability, leading to pancreatic insulitis development [60]

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Combined with our previous researches 15,16 , we concluded the penile length was improved by remodeling tunica albuginea

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10.1016/j.jacc.2018.09.042 55 TrujilloJ