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Kopple JD, Fouque D

The findings, published in the journal Science Advances , confirm that alpha cells in the pancreas can also release GLP-1 into the bloodstream after eating, helping to lower blood sugar by increasing insulin

Further, the researchers trained all participants to use syringes and single-dose pens, facilitating injecting study drugs on-site at randomization

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The VESPER program's mid-stage tolerability profile also carries indirect regulatory implications

As aforementioned, the reduced insulin response to incretins in patients with diabetes may theoretically pose a barrier to the effectiveness of incretin-based therapies