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, Lane, M

2022;doi:10.1016/S2468-1253(22)00213-8.

It is a G proteincoupled receptor that is distributed in various tissues, both centrally and peripherally (24, 25)
Boxed warning The boxed warning (often wrongly called a black box warning) shown in the image below notes that tirzepatide causes thyroid C-cell tumors in rats

Perkovic V, Tuttle KR, Rossing P et al

Contact your healthcare provider for guidance on monitoring and potential treatment adjustments