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106 Two additional clinical trials are being conducted to gather more data on adverse effects in different situations of liver injury, and a phase 2 trial investigating treatment effects for MASH with fibrosis based on histological assessment is ongoing (NCT05877547)

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Common Topamax side effects include: Nausea and diarrhea Dizziness, drowsiness, and trouble concentrating Numbness or tingling in the arms or legs Less common side effects that may be more severe include: Skin reactions, no matter how mild Vision problems, such as blurred vision Signs of kidney stones Symptoms of dehydration Allergic reaction Drinking alcohol with Topamax can lead to serious side effects like dehydration