glp-1 ghrelin Is a glucagon‐like peptide‐1 secretagogue? - Ueno - 2016 - Journal of Diabetes Investigation GLP-1 and ghrelin inversely regulate
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There is no reliable timeline, and it varies a lot from person to person

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While this leads to more consistent appetite suppression, it can result in prolonged, low-grade constipation or mild nausea that takes several weeks to fully resolve as the body adapts

Consequently, activation of these receptors produces a small but consistent chronotropic effect
