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This enhanced efficacy is due to its unique mechanism of simultaneous modulation of appetite, energy expenditure and insulin regulation pathways

doi: 10.1016/j.cmet.2019.07.013 58 BergmannNCLundAGasbjergLSMeessenECEAndersenMMBergmannSet al

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Approximately 15% to 20% of participants in the trials were high responders, achieving 30% or greater weight loss