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They lost about 8% of their body weight in 24 weeks.1 Individuals who gained back some weight after surgery lost almost 9% of their body weight after six months of taking liraglutide or semaglutide.2 People who had surgery and started gaining weight again lost about 10-15% of their weight after six months of taking semaglutide or tirzepatide.3 In summary, obesity is a complex disease that requires a variety of tools to manage it long-term

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This blog post by Hormone Fitness explains tirzepatide's unique mechanism of action in clear, easy-to-understand language

The validated method was applied to pharmacokinetic studies following intravenous (IV, 0.5 mg/kg) and subcutaneous (SC, 1 and 2 mg/kg) administration in rats