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Short-acting GLP-1 RAs Long-acting GLP-1 RAs Short-acting

[2] The safety profile of Orforglipron was consistent with existing GLP-1 therapies, with the most common adverse events being mild to moderate gastrointestinal symptoms such as diarrhea, nausea, dyspepsia, and constipation

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GLP-1 slows gastric emptying and gut motility, while both GLP-1 and GLP-2 have been shown to act as ileal brakes, slowing nutrient transit in the small intestine to facilitate nutrient absorption 76

Table of Contents What Is Saxenda and How Does It Work