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Activation of GLP-1 receptor and GIP receptor alters gastric emptying, intestinal motility, and gut secretions

Injection site reactions As Zepboud is injected into the skin of your upper arm, stomach, or thigh daily, you might have injection site reactions like irritation, bruising, redness, pain, or itching

Additionally, the structural properties of tirzepatide influence its side effect profile

45(Suppl 1): S144S174

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Reduced body weight after the combination of PIO with either GLP-1R agonists or SGLT2 inhibitors was also verified in a recent systematic review/meta-analysis, as well as an analysis of a large international real-world database [140]