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Physical activity guidelines for older adults

Transient receptor potential melastatin 5 (TRPM5) KO (B6;129- Trpm 5tm1Csz/J) mice were obtained from Jackson Laboratory ( Heterozygous Trpm5 +/ mice were bred to obtain age- and sex-matched homozygous wild-type (WT) and homozygous Trpm5 / mice

For the best results, you should avoid eating or drinking for 30 minutes before and after you take your dose

You and your healthcare team should determine what strategies are best for reducing your risk of heart disease

For analysis of circulating peptide hormones, data below the detection limit was considered as an outlier and omitted from data analysis

Abbreviations CVOTs: Cardiovascular outcome trials DPP-4 inhibitors: Dipeptidyl peptidase-4 inhibitors GLP-1RA: Glucagon-like peptide-1 receptor agonists SGLT-2 inhibitors: Sodium-glucose cotransporter 2 inhibitors MACE: Major cardiovascular events RR: Risk ratio HHF: Hospitalization for heart failure References IDF Diabetes Atlas 2021 10th edition