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[DOI] [PubMed] [Google Scholar] 39.Petrou M, et al
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This prompted the transfer of the MDL to U.S

Severe or end-stage kidney disease usually needs specialist input before starting

If you have any serious side effects like severe stomach pain, dehydration, or symptoms of low blood sugar like dizziness and blurred vision, stop taking the medication and contact your healthcare provider

Even so, the broad alignment between reported gastrointestinal effects and established safety profiles has lent credibility to the approach, while the emergence of less well-documented symptoms has highlighted potential gaps in current understanding

Common adverse events included diarrhea, vomiting, and constipation (more common for those on the highest dose)
