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In 2019, the REWIND trial found that in the 9901 patients with T2DM with and without previous CVD randomly assigned to a once-weekly 1.5 mg dulaglutide injection or placebo (median follow-up 5.4 years), three-point MACE occurred in 594 patients receiving dulaglutide (12.0%) and in 663 patients (13.4%) in the placebo group, which included a significant decrease in the rate of non-fatal stroke (Gerstein et al

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Of the 316 participants included in this study, the mean (standard deviation) age was 59.9 (9.1) years, 213 (67.4%) were male, and 78 (24.7%) were Hoehn and Yahr Stage I