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The combination with GLP-1 also appears to reduce the gastrointestinal side effects that sometimes limit GLP-1 only treatments, improving tolerance and long-term adherence

TRIUMPH (obesity-focused, 4 core registrational trials) has TRIUMPH-1 and TRIUMPH-4 complete, with TRIUMPH-2 (obesity+diabetes) and TRIUMPH-3 (obesity+cardiovascular disease) expected later in 2026

Journal of Clinical Oncology, 25(25), 3781-3787

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