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doi: 10.1111/dom.13025

Safety and efficacy of Efruxifermin in combination with a GLP-1 receptor agonist in patients with NASH/MASH and type 2 diabetes in a randomized phase 2 study

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In the S 2 pocket, an aromatic heterocyclic ring or substituted fused rings are preferred

This was a landmark moment because it represented global recognition of GLP-1 medications as a legitimate long-term treatment for obesity rather than a temporary or supplementary intervention