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The FDA subsequently classified AOD-9604 within Category 2 of the bulk drug substance review process, and the compound was later withdrawn from that nomination in April 2026

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Both carry the same warnings for pancreatitis, gallbladder problems, and kidney injury from getting dehydrated, and both flag low blood sugar if you pair them with insulin or a sulfonylurea diabetes drug

Ianiro G, Bibbo S, Bruno G, et al

It is more effective than antacids for preventing reflux rather than just treating it

The proportion of missing data were substantial (greater than 20%) and differential between SEM and the controls in most of the trials