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Although long-term safety and efficacy require further evaluation, current evidence positions GLP-1 RAs as promising therapeutic agents in translational geroscience, with the potential to mitigate age-related physiological decline and promote a longer, healthier lifespan.

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But despite rising rates of diabetes and obesity, access to these medicines remain limited in South Africa, writes Catherine Tomlinson for Spotlight, who finds out which of the GLP-1 agonists are []