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In that setting, the problem is often not undertreatment
Clinical Evidence and Efficacy Several clinical trials have demonstrated the efficacy of Ozempic in promoting weight loss

GLP-1 injections may help fix that by reducing inflammation in the brain, improving how insulin works in the body, while boosting the brain's metabolism

Importantly, the weight loss was sustained, suggesting long-term benefits for health and longevity
- Bursor & Fisher, P.A

The mechanism is fascinating: Unlike GLP-1 agonists that work on gut hormones, tesofensine directly modulates brain neurotransmitters controlling appetite and energy expenditure
