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Apart from this, the reduction in matrix metalloproteinase-1 (MMP-1) levels mediated by GLP-1RA attenuates the proliferative capacity of cancer cells

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The downstream pathways are mainly the PI3K and MAPK pathways

Molecular and Cellular Neuroscience DOI:10.1016/j.mcn.2026.104091 Abstract The effects of GLP-1 receptor agonists on Alzheimers pathophysiology: A systematic review Background The incidence of Alzheimers disease (AD) is increasing globally but there are limited effective therapies available

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In addition, we used protein immunoprecipitation to verify the interaction between GLP-1R and the PKA/CREB pathway