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Staying active is another good strategy, as physical activity helps improve circulation and generate body heat

Why you should care: In a rigorous 6-month placebo-controlled trial, a specific, identified strain showed measurable differences in body fat and energy intake

Most side effects, especially gastrointestinal ones, tend to improve within a few weeks as your body adjusts to the medication

Mechanism differences that matter Beyond the weight loss numbers, the glucagon receptor component gives retatrutide properties that semaglutide and tirzepatide lack

Keeping these levels balanced is the key to eliminating diabetes symptoms, lowering risk for heart complications, and aiding weight loss

Similarly, Wegovy (semaglutide) is FDA-approved to reduce the risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease and obesity or being overweight