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Description
This GLP-R1 agonist seems to increase oncogenesis in multiple tissues, including the thyroid, bladder, pancreatic, and colorectal [97, 110, 121]
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Potential Side Effects and Safety Considerations Semaglutide is well-tolerated in most patients, but common early side effects include mild nausea, constipation, or decreased appetite (which is actually the therapeutic goal)
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Rybelsus is prescription-only and has been available in Germany since July 2025
