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After a 4-week run-in period in which participants were treated with diet and exercise alone, those who fulfilled the randomisation criteria were randomised (1:1:1:1) using a web-based randomisation system to receive once-daily oral semaglutide 3 mg, 7 mg or 14 mg or placebo for 26 weeks (using a 4-week dose-escalation regimen for the higher doses)
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In recent years, the spotlight has shifted towards foods that naturally promote the production of GLP-1, a hormone that plays a crucial role in regulating appetite and blood sugar levels

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The model is easy and affordable to replicate, opening the door for global research into smell loss tied to COVID-19, aging, or diseases like Parkinson s.
