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Over time, the GLP-1 population has evolved to include an increasing prevalence of patients with no prior antidiabetic prescriptions and with fewer diabetes diagnoses

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Researchers found that participants who took Zepbound for 18 months lost more weight (20.2% of their body weight, or an average of about 50 pounds) compared to those on Wegovy (13.7% of their body weight, or about 33 pounds on average)

Exenatide alters myocardial glucose transport and uptake depending on insulin resistance and increases myocardial blood flow in patients with type 2 diabetes
It aims to tailor drug therapy for every patient based on their unique genetics and how they will respond to certain medications

Most of the subjects included in the available RCTs are PCOS patients with severe obesity, which do not reflect the entire clinical spectrum of PCOS encountered in clinical practice