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In addition to reducing the cholesterol content of plaque, lipid lowering reduces the accumulation of macrophages, which produce proteolytic enzymes, such as matrix metalloproteinases (MMPs, especially MMP-1, MMP-2, MMP-3, MMP-9, and MMP-13) [13]

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However, it is essential to understand these mechanisms to effectively manage potential side effects, including fatigue, particularly in relation to whether does GLP-1 make you tired that some patients may encounter during treatment

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doi: 10.1111/ECI.14334 [DOI] [PubMed] [Google Scholar] 37.Zhang H-D, Yu F-Y, Ding L, et al