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In the parent study, 24 weeks of low-dose semaglutide (1 mg subcutaneously weekly) significantly reduced IHTG by 31.3%, improved insulin sensitivity (approximately 1.5-unit decrease in Homeostatic Model Assessment of Insulin Resistance (HOMA-IR)), and lowered triglyceride levels by 27 mg/dL 12

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[94] However, significant corticosteroid activity may still reach the developing fetus and could potentially affect fetal development

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Table of Contents What Are Incretin Mimetics and How Do They Work