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Some researchers wonder if the same thing might affect the optic nerve in people taking GLP-1 drugs

A: I empathize and agree with your point

This is well presented
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Exercise studies in healthy young men showed that skeletal muscle MOTS-c levels increase nearly 12-fold after acute exercise, suggesting this peptide mediates some of the metabolic benefits of physical activity

But a closer look at their origins reveals a far less conventional story than most modern drugs