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Pozzi, M

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Controlling the global obesity epidemic

There are situations where adjustments are necessary

For instance, central administration of liraglutide, an analog with a long half-life, activates GLP-1R in the ventromedial nucleus of the hypothalamus (VMH), triggering AMP-activated protein kinase (AMPK) inhibition and leading to sympathetic-induced BAT thermogenesis and browning of WAT, as well as reduced food intake [97]

Cardiovascular Health in the Canadian Context Canada faces unique cardiovascular health considerations that make Retatrutides benefits particularly relevant