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In most major obesity trials, GLP-1 therapy was: Escalated to high or maximum tolerated doses Stopped abruptly, not down-titrated Followed by little or no continuation of structured lifestyle support In the STEP-1 extension trial (semaglutide 2.4 mg), participants who discontinued therapy regained approximately two-thirds of their prior weight loss over the following year

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The rise of GLP-1 therapies marks a turning point in how obesity itself is understood

This webinar with obesity medicine physician Jonathan Bonnet, MD, MPH, a GLP-1RA expert, will answer all your questions about the medications, how they work, their benefits, their side effects, and how they can be combined with lifestyle changes to optimize your weight loss and body composition.

The federal government is expected to start a 5-year-long experiment that will provide some limited coverage of obesity medications.