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In England, estimates of up to 400,000 people have been affected by the GLP-1 RA shortage (Seth, 2024)

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Pregnancy and Breastfeeding: Most GLP-1 weight loss studies do not allow participation from pregnant or breastfeeding women due to unknown risks to the baby and potential hormonal effects

In summary, these strategies support the preservation of lean mass, functional capacity, and safety in older adults, while enabling the mitochondrial, metabolic, and broader healthspan-supporting benefits of GLP-1 RAs

For men who need TRT but aren't ready to close the door on fatherhood, this combination offers a middle path

The Alleviating Effect and Mechanism of GLP-1 on Ulcerative Colitis