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Clinical Significance: The 2025 updates reaffirm that while HbA1c remains central, a one-number-fits-all strategy is outdated
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However, inhibition of DPP-4 also potentiates the stem cell chemokine, stromal cell-derived factor-1 (SDF-1), which can promote inflammation, proliferative responses and neovascularization
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The study findings may spark treatment innovations for depression and anxiety.
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