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Ozempic vs Standard PCOS Treatments While metformin remains the first-line FDA-approved treatment for PCOS with insulin resistance, GLP-1 medications like Ozempic generally result in greater weight loss and better metabolic improvement in patients with severe insulin resistance

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Consequently, once-daily subcutaneous administration of liraglutide 3.0 mg was developed for the treatment of obesity [21] and once-weekly subcutaneous administration of semaglutide 2.4 mg is currently being investigated in phase III trials for this indication [22]

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Why Do GLP-1s Cause Nausea