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In clinical trials, GLP-1 RAs were shown to significantly lower blood pressure (BP) in addition to HbA1c and body weight (BW), indicating the possibility as anti-hypertensive medication of type 2 DM individuals

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Screen patients for personal or family history before prescribing GLP-1 RAs. The benefits of GLP-1 RAs on cardiovascular health may outweigh any small increase in absolute risk of thyroid cancer.

Experts are raising concerns about a lesser-known GLP-1 side effect.