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For women who desire future pregnancies, preconception evaluation is important to determine if valve intervention is indicated prior to conceiving. Show notes What is the epidemiology of valvular heart disease in pregnancy

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However, a lack of GLP-1R is also observed to trigger a stress response that boosts fibroblast growth factor 21 and elicits beneficial systemic effects such as memory improvement and glucose homeostasis (Timper et al., 2020)

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This typically involves annual TSH testing, though more frequent monitoring may be necessary if thyroid medication doses are being adjusted