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Not using supplements alongside GLP-1 medications can lead to several potential issues

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However, inhibition of DPP-4 also potentiates the stem cell chemokine, stromal cell-derived factor-1 (SDF-1), which can promote inflammation, proliferative responses and neovascularization

That same year, the American Diabetes Association updated its guidelines to make GLP-1s a first-line therapy for type 2 diabetesfurther increasing demand

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Rationale Obesity remains a major global health challenge, severely affecting metabolic and cardiovascular health
