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Berberine is a bitter-tasting yellow-colored substance found in plants such as goldenseal, Monti says

It works by helping regulate blood sugar levels through increased insulin release and slowed gastric emptying, and it is administered as a once-daily injectable medication

doi: 10.1186/s13063-019-3259-x [DOI] [PMC free article] [PubMed] [Google Scholar] 202.Egefjord L, Gejl M, Mller A, et al

It is a GLP-1 and GIP receptor agonist

Magnetic resonance imaging-based three-dimensional bone shape of the knee predicts onset of knee osteoarthritis: data from the osteoarthritis initiative
