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GLP-1 receptor agonists such as semaglutide (marketed under brand names Ozempic, Wegovy, and Rybelsus) and the dual GIP/GLP-1 agonist tirzepatide (marketed under brand names Mounjaro and Zepbound) are FDA-approved prescription medications for specific uses in type 2 diabetes management and, in some cases, chronic weight management

[1] [5] These gastrointestinal effects typically diminish over time as the body adjusts to the medication

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NHS Guidance on GLP-1 Injection Timing The NHS and NICE provide evidence-based guidance on GLP-1 receptor agonist use, though specific recommendations on timing generally align with manufacturer instructions rather than prescriptive clinical protocols