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The LEADER trial with liraglutide and the REWIND trial with dulaglutide did not show significant increases in retinopathy complications, though differences in trial design, patient populations, baseline retinopathy prevalence, and rates of glycemic improvement may explain these discrepant findings

The key is staying in communication with your prescriber rather than trying to self-adjust either medication

Endocr Rev 44(1):1432 Yang SH, Xu RX, Cui CJ, Wang Y, Du Y, Chen ZG, Yao YH, Ma CY, Zhu CG, Guo YL, Wu NQ, Sun J, Chen BX, Li JJ (2018) Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism

Neural responsivity to food cues in fasted and fed states pre and post gastric bypass surgery

Injection technique: Inject slowly and steadily

In order to make GLP-1 better used in the clinic, drug developers modified its structure and developed a series of GLP-1R agonists (13)