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Goraya N, Raphael KL, Wesson DE

GLP-1 (glucagon-like peptide 1) is one of these hormones, and it has a big role in appetite

This finding was replicated in nonhuman primates using another antibody, now against the human GIP receptor, supportive of an antagonistic approach for obesity treatment (54)

The FLOW trial, a double-blind, placebo-controlled study examining renal outcomes in patients with type 2 diabetes and chronic kidney disease, demonstrated that semaglutide reduced the progression of kidney disease by 24% compared to placebo

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Subsequently, patients are advised to escalate their intake by increasing the dosage to a daily measurement of 7 mg3
