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Description
8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes

do not use it if you or a family member has had medullary thyroid carcinoma or MEN 2

Understanding this context does not excuse misleading marketing, but it does explain the demand
Lakhani M, Kwan AT, Mihalache A, et al

Health Affairs (Project Hope), 43 (11), 14911501

Extending its duration of action has become a focus of drug development