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These effects could improve cardiovascular and metabolic outcomes, making GLP-1 RAs more beneficial for PD patients with metabolic comorbidities
Most patients experience improvement in symptoms after 48 weeks of continued treatment as physiological adaptation occurs

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Yes, it is

Injectable effectiveness rates are higher than oral with studies, showing 20% and higher body weight lossbut the shots cost $1,000 per month or more
Switching between morning and evening injections weekly can create fluctuations in hormone signaling and may reduce the smoothness of appetite suppression
