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Monitoring blood glucose levels closely is essential when starting or changing doses of tirzepatide with other diabetes medications

For example, a study of 62 children with chronic liver disease and 27 healthy controls found serum biotinidase activity to be abnormally low in those with severely impaired liver function due to cirrhosis (14)

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Tirzepatide triggers little of that wind-down signal, which helps each engaged receptor keep signaling

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