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Clinical trials consistently show meaningful reductions in caloric intake and body weight among individuals using these therapies (Davies et al., 2021

The effect is impressive however, long-term consequences are not yet fully researched

These guidelines emphasize that obesity medications should be continued as long as they remain effective, are well-tolerated, and the benefits outweigh risks

On the episode titled Peptide and Hormone Therapies for Health, Performance & Longevity, Craig Koniver, MD, a physician who specializes in performance medicine protocols, described his low and slow approach: He prescribes patients small compounded doses of semaglutide and tirzepatide to help them lose weight at a gradual pace and minimize muscle loss and side effects such as nausea and Ozempic face. Microdosing has been a game changer, Dr

While many different physicians can prescribe GLP-1s, TMH houses the only surgical center in the region that has earned accreditation through the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP), a joint quality program of the American College of Surgeons (ACS) and the American Society for Metabolic and Bariatric Surgery (ASMBS)

From there, the dose is typically increased to 4 mg, then 8 mg, with 12 mg as the commonly studied maximum weekly dose