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Description
The burden of CKD resulting from T2D, quantified with disability and mortality risk measures, has increased since 1990, mostly due to population expansion and ageing [2]

The tirzepatide label for Zepbound specifically notes that weight loss offers no benefit to a pregnant patient and may cause fetal harm

Rita Kapoor MD , ensuring safe and effective treatment for weight loss
Since albumin does not cross the hemochorial placenta, as shown in the rat (60), guinea pig (61) and in vitro in a human placenta (62), it seems unlikely that the albumin fusion protein albiglutide should cross the placenta

Impact of maternal pre-pregnancy body mass index on maternal, fetal and neonatal adverse outcomes in the worldwide populations: a systematic review and meta-analysis
Tsai, W.-H
