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In brain centers, LepRs were found in GLP-1Rexpressing neurons in the nucleus of the solitary tract and leptin was found to stimulate these neurons (113, 114)

For diabetic patients this creates challenges, as individuals who really benefit from these therapies are having a tough time obtaining the treatment they need

Side Effects of Retatrutide vs Zepbound Both Retatrutide and Zepbound share a similar side effect profile, which is common across GLP-1 based medications

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61 Specific case studies identified additional side effects due to exenatide extended-release injections

These side effects should decrease over time as your body adjusts to the medication