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Med 214 , 193205 (2024)

Clinical trial benchmarks by timeframe The SURMOUNT trials provide gold standard benchmarks for expected outcomes

Third-Party Data & External Sources This report may rely on data from third-party sources believed to be reliable

Nearly all these medications are administered by weekly injection, though there is one semaglutide oral tablet (Rybelsus) approved for diabetes

In the tirzepatide trial, participants lost an average of 6.9% of their weight after 12 weeks, while retatrutide participants lost 7.2% at the lowest dose after 24 weeks
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