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However, it has been shown to be very effective in helping patients with overweight or obesity lose weight, and is sometimes prescribed off-label for weight loss

Case reports and expert opinion pieces were initially excluded, to maintain a higher level of evidence

Compounded semaglutide costs $299 per month

The theoretical mechanism involves reduced stomach acid, but clinical significance remains unclear

The company announced this week it will begin offering compounded semaglutide for $199 per month, starting immediately for US consumers

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