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Collectively, these data reveal that exendin 2029 acts as a key sequence in inducing analgesia in CAP-elicited nociceptive behaviors in mice without causing hyperthermia, and this analgesic effect is mediated by exendin 2029 directly inhibiting CAP-induced TRPV1 activation but not proton-induced TRPV1 activation

doi: 10.1016/j.yfrne.2013.08.001 202 GollapudiLOblingerMM

doi: 10.4103/aian.aian_533_22

However, some healthcare professionals have prescribed Rybelsus off-label for weight management, especially if a patient is opposed to injections

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