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References: Romantsova, T

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GIP receptor activation contributes to enhanced insulinotropic effects, while GLP-1 receptor activation supports weight reduction and metabolic improvements

The researchers used the TriNetX research network to analyze outcomes for 496,756 patients who initiated GLP-1RA therapy

He does highlight as a negative the fact that semaglutide is given once per week as a subcutaneous injection, and suggests that it will be beneficial if the oral version currently under investigation is found to be effective

This will be achieved through meticulous synthesization of existing RCTs to offer a thorough evaluation of the prevalence and severity of GI side effects that come with tirzepatide and semaglutide treatment